10
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T1889 | CP-640186 | CP 640186 | Acetyl-CoA Carboxylase |
CP-640186 is an isozyme-nonselective Acetyl-CoA carboxylase (ACCase) inhibitor. The IC50s of CP-640186(CP 640186) is 53 nM and 61 nM for rat liver ACC1 and rat skeletal muscle ACC2 respectively. | |||
T3622 | CP-640186 hydrochloride | CP 640186 HCl | Acetyl-CoA Carboxylase |
CP-640186 hydrochloride (CP 640186 HCl) is an isozyme-nonselective acetyl-CoA carboxylase (ACC) inhibitor, including rat liver ACC1 (IC50: 53 nM) and rat skeletal muscle ACC2 (IC50: 61 nM); with higher metabolic stabilit... | |||
T27753 | KT-362 fumarate | KT 362,KT362,KT-362 | Potassium Channel , Calcium Channel , Sodium Channel |
KT-362 fumarate is a novel compound that acts as an antagonist of calcium channels, potassium channels and sodium channels.KT-362 fumarate causes vasodilation by affecting intracellular calcium mobilization in atrial mus... | |||
T37459 | Lipoxin A5 | ||
Lipoxin A5 (LXA5) is produced by enzymatic transformation of EPA by leukocytes. LXA5 slowly contracts pulmonary parenchymal strips from guinea pig with similar potency to that of LXA4 and LXB4. However, LXA5 does not exe... | |||
T76430 | GR 87389 | ||
GR 87389, a potent NK2 receptor antagonist, competitively inhibits GA 64349-induced contractions in smooth muscle strips of the human detrusor, prostate, and prostatic urethra [1] [2]. | |||
T3074L | CHIR98014 HCl (252935-94-7 free base) | CT-98014,CHIR-98014 hydrochloride,CHIR-98014,CHIR98014 HCl,CHIR98014,CHIR 98014 | |
CHIR98014 is a reversible, cell-permeable inhibitor of GSK3α and GSK3β (IC50s: 0.65 and 0.58 nM). Through its effects on GSK3, CHIR98014 stimulates glycogen synthase in cells (EC50: 106 nM), potentiates insulin-dependent... | |||
T35787 | Obestatin (human) (trifluoroacetate salt) | ||
Obestatin is a 23 amino acid peptide hormone with a conserved C-terminal glycine residue and amidation site that is formed by cleavage of the ghrelin and obestatin prepropeptide.1It binds to the orphan receptor GPR39 (Kd... | |||
T37620 | Leukotriene C4 methyl ester | ||
Leukotriene C4 (LTC4) is the parent cysteinyl-leukotriene produced by the LTC4 synthase-catalyzed conjugation of glutathione to LTA4. LTC4 is produced by neutrophils, macrophages, and mast cells, and by transcellular met... | |||
T83905 | Brain Natriuretic Peptide-32 (rat) acetate | BNP (14-45),B-type Natriuretic Peptide-32,Brain Natriuretic Polypeptide-32,BNP-32 | |
Brain natriuretic peptide-32 (BNP-32), a fragment of the proBNP cardiovascular hormone precursor, exhibits affinity for natriuretic peptide receptors in rat vascular smooth muscle cells (IC50 = 7.3 nM) and promotes cGMP ... | |||
T35597 | Neuromedin U-23 (rat) (trifluoroacetate salt) | ||
Neuromedin U-23 (NMU-23) is a neuropeptide involved in diverse biological processes, including smooth muscle contraction, energy homeostasis, and nociception.1It is an agonist of neuromedin-U receptor 1 (NMUR1; EC50= 0.1... |